Background and objectives: The purposes of this study were to demonstrate that laser soldering is safe and effective for tissue bonding in dural reconstruction and to compare this new reconstruction technique to an established one. Study design: A temperature-controlled fiberoptic CO2 laser system or fibrin glue were used for in vitro dural defect reconstruction in two groups of pigs. The CO2 laser technique was also used for dural reconstruction in live pigs. Results: The burst pressure of the reconstructed dura by the laser system was significantly higher than that of fibrin glue (mean pressure 258.5 ± 117.3 cm H2O and 76.8 ± 47.2 cm H2O, respectively). There were no postoperative complications and no signs of thermal damage to the dura, fascia, or underlying tissue on histological analysis following the in vivo CO2 laser experiments. Conclusions: Temperature-controlled laser soldering is an effective technique for dural repair. It creates a strong tissue bonding with no thermal damage to the tissue. The burst pressure of the reconstructed dura done with laser soldering is significantly higher than that of fibrin glue.
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机译:背景与目的:这项研究的目的是证明激光焊接对硬脑膜重建中的组织粘合是安全有效的,并将这种新的重建技术与已建立的技术进行比较。研究设计:使用温度可控的光纤CO2激光系统或纤维蛋白胶在两组猪中进行硬脑膜外缺陷重建。 CO2激光技术还用于活猪的硬脑膜重建。结果:激光系统重建硬脑膜的破裂压力显着高于纤维蛋白胶(平均压力分别为258.5±117.3 cm H2O和76.8±47.2 cm H2O)。在体内CO2激光实验后的组织学分析中,没有术后并发症,也没有对硬脑膜,筋膜或下层组织造成热损伤的迹象。结论:温控激光焊接是一种有效的硬膜修复技术。它建立了牢固的组织结合力,而对组织没有热损伤。用激光焊接完成的硬脑膜的破裂压力显着高于纤维蛋白胶的破裂压力。
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